Senior Manager, Regulatory Affairs salary in Massachusetts
A real-employer view of Senior Manager, Regulatory Affairs pay, clustered from DOL OFLC certified filings. Variants like Senior, Lead, and II/III titles fold into this cluster — the wage range below reflects all of them.
Senior Manager, Regulatory Affairs in Massachusetts: actual employer-disclosed pay
Public records from 22 certified H-1B Labor Condition Applications filed with the U.S. Department of Labor. Median offered wage: $158,961. Every figure below is an actual offered salary an employer attested to under federal law.
By DOL wage level
DOL classifies every offer into one of four wage levels based on the role's experience and skill requirements.
| Level | Filings | Median offer |
|---|---|---|
| Level I — entry | 6 | $136,674 |
| Level II — qualified | 10 | $156,431 |
| Level III — experienced | 4 | $187,075 |
Top employers filing for this role
Companies with the most certified filings for Senior Manager, Regulatory Affairs in Massachusetts. Median offer is across all of that employer's filings. Click a company for its full H-1B salary breakdown.
| Employer | Most-filed title | Filings | Median |
|---|---|---|---|
| Takeda Development Center Americas, Inc. | Senior Manager, Global Regulatory Affairs | 5 | $160,060 |
| Apellis Pharmaceuticals Inc. | Manager, Regulatory Affairs | 2 | $148,492 |
| Karyopharm Therapeutics Inc. | Senior Manager, Regulatory Operations | 2 | $189,358 |
| Rhythm Pharmaceuticals Inc. | Senior Manager, Regulatory Affairs | 2 | $165,000 |
| Alkermes, Inc. | Senior Manager, CMC Regulatory Affairs | 1 | $152,000 |
| Alnylam US, Inc. | Manager, Regulatory Affairs, CMC Development | 1 | $130,000 |
| argenx US, Inc. | Senior Manager, Gcp Quality | 1 | $185,650 |
| Beam Therapeutics, Inc. | Senior Manager, Regulatory Affairs | 1 | $155,000 |
| Blueprint Medicines Corporation | Manager, PV Validation | 1 | $157,862 |
| Collegium Pharmaceutical, Inc. | Manager, Regulatory Affairs | 1 | $177,382 |
Recent sample filings
A snapshot of recent certified offers. Each line is a real, public, verifiable record.
- Senior Manager, Regulatory Operations at Karyopharm Therapeutics Inc.$190,215NewtonWage Level IIIDecided Mar 27, 2026I-200-26079-718687
- Manager, Regulatory Affairs at Collegium Pharmaceutical, Inc.$177,382StoughtonWage Level IIDecided Mar 24, 2026I-200-26076-709784
- Senior Manager, CMC Regulatory Affairs at Alkermes, Inc.$152,000WalthamWage Level IDecided Jan 22, 2026I-200-26014-558770
- Manager, Regulatory Affairs at CRISPR Therapeutics, Inc.$1,524,000BostonWage Level IDecided Nov 7, 2025I-200-25306-356583
- Manager, PV Validation at Blueprint Medicines Corporation$157,862CambridgeWage Level IIDecided Sep 9, 2025I-200-25245-281018
- Senior Manager, CMC Development & Project Management at Syner-G BioPharma Group LLC$143,220FraminghamWage Level IDecided Aug 19, 2025I-200-25224-236363
- Senior Manager, Regulatory Affairs at Mercy BioAnalytics, Inc.$130,127WalthamWage Level IDecided Jul 29, 2025I-200-25203-191479
- Senior Manager, Global Regulatory Affairs Marketed Products at Takeda Development Center Americas, Inc.$160,140CambridgeWage Level IIDecided Jul 16, 2025I-200-25190-163684
Source: U.S. Department of Labor, Office of Foreign Labor Certification. Disclosed wages reflect what employers attested to pay; actual paid wages may differ. Only certified filings are shown — denied and withdrawn cases are excluded.