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Specialty Profile · Massachusetts

Senior Manager, Regulatory Affairs salary in Massachusetts

A real-employer view of Senior Manager, Regulatory Affairs pay, clustered from DOL OFLC certified filings. Variants like Senior, Lead, and II/III titles fold into this cluster — the wage range below reflects all of them.

Adrian Serafin, founder and editor of RateOrchardBy Adrian SerafinFounderUpdated May 4, 2026
Real disclosed salaries

Senior Manager, Regulatory Affairs in Massachusetts: actual employer-disclosed pay

Public records from 18 certified H-1B Labor Condition Applications filed with the U.S. Department of Labor. Median offered wage: $156,431. Every figure below is an actual offered salary an employer attested to under federal law.

By DOL wage level

DOL classifies every offer into one of four wage levels based on the role's experience and skill requirements.

LevelFilingsMedian offer
Level I — entry4$130,064
Level II — qualified9$155,000
Level III — experienced2$184,275

Top employers filing for this role

Companies with the most certified filings for Senior Manager, Regulatory Affairs in Massachusetts. Median offer is across all of that employer's filings.

EmployerMost-filed titleFilingsMedian
Takeda Development Center Americas, Inc.Senior Manager, Global Regulatory Affairs, Marketed Products5$160,060
Apellis Pharmaceuticals Inc.Manager, Regulatory Devices2$148,492
Rhythm Pharmaceuticals Inc.Senior Manager, Regulatory Affairs2$165,000
CRISPR Therapeutics, Inc.Manager, Regulatory Affairs1$1,524,000
Blueprint Medicines CorporationManager, PV Validation1$157,862
Syner-G BioPharma Group LLCSenior Manager, CMC Development & Project Management1$143,220
Mercy BioAnalytics, Inc.Senior Manager, Regulatory Affairs1$130,127
Intellia Therapeutics, Inc.Senior Manager, Regulatory Affairs1$182,900
argenx US, Inc.Senior Manager, Gcp Quality1$185,650
Beam Therapeutics, Inc.Senior Manager, Regulatory Affairs1$155,000

Recent sample filings

A snapshot of recent certified offers. Each line is a real, public, verifiable record.

  • Manager, Regulatory Affairs at CRISPR Therapeutics, Inc.
    $1,524,000
    BostonDecided Nov 7, 2025I-200-25306-356583
  • Manager, PV Validation at Blueprint Medicines Corporation
    $157,862
    CambridgeWage Level IIDecided Sep 9, 2025I-200-25245-281018
  • Senior Manager, CMC Development & Project Management at Syner-G BioPharma Group LLC
    $143,220
    FraminghamWage Level IDecided Aug 19, 2025I-200-25224-236363
  • Senior Manager, Regulatory Affairs at Mercy BioAnalytics, Inc.
    $130,127
    WalthamWage Level IDecided Jul 29, 2025I-200-25203-191479
  • Senior Manager, Global Regulatory Affairs Marketed Products at Takeda Development Center Americas, Inc.
    $160,140
    CambridgeWage Level IIDecided Jul 16, 2025I-200-25190-163684
  • Senior Manager, Regulatory Affairs at Intellia Therapeutics, Inc.
    $182,900
    CambridgeWage Level IIIDecided May 13, 2025I-200-25126-942521
  • Senior Manager, Gcp Quality at argenx US, Inc.
    $185,650
    BostonWage Level IIIDecided Mar 13, 2025I-200-25065-749342
  • Senior Manager, Regulatory Affairs at Beam Therapeutics, Inc.
    $155,000
    CambridgeWage Level IIDecided Mar 12, 2025I-200-25065-748737

Source: U.S. Department of Labor, Office of Foreign Labor Certification. Disclosed wages reflect what employers attested to pay; actual paid wages may differ. Only certified filings are shown — denied and withdrawn cases are excluded.